Wrist and hand problems rarely occur in isolation, unless they are the result of a traumatic injury, and even then the likelihood is that there will be an impact on the functioning of other structures. This is unsurprising when you consider that the whole upper extremity is designed to position the hand in space, so poor function in one area is bound to have a knock on effect elsewhere. When you rotate your wrist you rely on a joint just next to the main elbow joint and you use muscles located in the forearm and, believe it or not, your biceps muscle. The nerve supply to the hand passes from the neck and shoulder and right through the arm. Problems with the wrist and hand require a wide perspective.